An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. It may be either. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar. ameloblastic fibroma in a 9-year-old boy has been presented along with a review of the literature. The tumor responded to conservative surgical treatment.

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Unilocular lesions are predominantly asymptomatic, while the multilocular cases are often associated with jaw swelling [ 8 ]. Published online Dec 1.

The epithelial islands, nests, and strands were composed of peripheral tall columnar hyperchromatic cells exhibiting reversal of polarity and loosely arranged central cells having angular to spindle shape.

In the present report, the presence of thin septa producing a stepladder pattern resembled that observed in myxoma, although odontogenic myxoma occurs most commonly in patients during third and fourth decades of life Ameloblastic fibroma AF is an extremely rare benign odontogenic tumor with a relative frequency between 1.

A fine-needle aspiration case report. Report of a case with a special reference to its aspiration cytologic findings. J Oral Maxillofac Surg. Ameloblastic fibrosarcoma of the mandible: In addition, orthodontic treatment was initiated Fig.

Pathology Outlines – Benign tumors / tumor-like conditions: ameloblastic fibroma

The amount and density of the epithelial component may vary from region to region within the same tumor. Patient had identified the enlargement 8 months back and ameloblastjc medical history was unremarkable.


Radiographically, ameloblastic fibromas are unilocular lesions, occasionally multilocular when larger, with smooth well-demarcated borders. Ameloblastic fibroma, cytopathology, fine-needle aspiration, mandible.

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Microscopically the epithelial component occupies the mesenchymal stroma in various patterns like thin long strands, cords, nests, or islands. These flbroma underscore the need for a complete excision of the tumor as well as long-term clinical and radiographic follow up, with special attention given to cases of recurrences, which have a greater risk of malignant transformation 4.

Odontogenic tumors Neoplasm stubs. Ameloblastic fibroma AF is an extremely rare true mixed benign tumor that can occur either in the mandible or maxilla. The tumors are considered a tumor of childhood and adolescence and occur almost exclusively in the first and second decades of life [ 34 ]. View at Google Scholar A. Fibrona information Article notes Copyright and License information Disclaimer.

Microscopically, an ameloblastic fibroma is composed of a connective tissue background that appears to recapitulate dental papilla, resembling stellate reticulum [ 137 ]. Based on the clinical and roentgenographic findings, a presumptive preoperative diagnosis of odontogenic tumor was made.

Ameloblastic fibroma in six-year-old male: Reported cases of ameloblastic fibromas with aspiration cytologic findings Click here to view. Medullary carcinoma of the breast Medullary thyroid cancer. The appropriate treatment for AF remains matter of debate.

In this brief report, we report a case of AF in the context of its high cellularity on histopathological examination. Surgical excision or thorough curettage with removal of affected teeth is the treatment of choice [ 12 ].


While uncommon, the possibility of malignant transformation of ameloblastic fibroma into ameloblastic fibrosarcoma is well documented [ 89 ]. To receive news and publication updates for Case Reports in Pediatrics, enter your email address in the box below. The lesion presented a firm consistency and no signs of inflammation were observed.

Ameloblastic fibroma: A rare case appearing as a mixed radiographic image

The surgical specimen was fixed in formalin and sent for histopathological analysis, which revealed an odontogenic tumor formed by islands of epithelial cells, with the columnar peripheral cells showing nucleus in inverted polarization.

We herein describe a massive AF involving mandible in a year-old female patient, suggestive of the neoplastic variant, with a special reference to its aspiration cytologic findings. Advanced Search Users Online: Histopathological differential cibroma include odontogenic myxoma and odontogenic fibroma.

There are two variants fibrpma AF: The least differentiated lesion, ameloblastic fibroma, actually occurs, on average, at an older age then the more differentiated ameloblastic fibro-odontoma and odontoma [ 4 ]. Review of the literature and presentation of new cases of odontomas.

National Center for Biotechnology InformationU. World Health Organization Classification of Tumours: For these reasons, despite many similarities, it is essential to differentiate the ameloblastic fibroma from other mixed odontogenic lesions because it has true neoplastic qualities.