Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Clinical examination reveals a firm and friable mass in the nasopharynx and nose.

Management of Juvenile Nasopharyngeal Angiofibroma: A Five Year Retrospective Study

Pterygopalatine fossa was invaded in 3 patients. Juvenile nasopharyngeal angiofibromas are benign but highly vascular tumours. Bony erosion of the nasal cavity, hard palate and pterygoid angiofibroam is also common. Thus this approach is best utilized for JNA confined to nasopharynx and sphenoid sinus. Diagnostic and therapeutic management. InFriedberg called it juvenile angiofibroma. Steroid hormone receptor expression in nasopharyngeal angiofibromas.

Hamid Abdul Qaiyum 1 Department of E. Conclusion Juvenile nasopharyngeal angiofibroma or nasopharyngeal angiofibroma is an uncommon disease of angiofjbroma adolescents.

Nasopharyngeal angiofibroma – Wikipedia

A wait and watch policy with periodic imaging may thus postpone or eliminate the need for surgery and reduce morbidity. Read it at Google Books – Find it at Amazon. However, most authors agree that JNAs arise from the nwsofaring choanal tissues in the region of the sphenopalatine foramen.


Thank nwsofaring for updating your details. Four patients had conductive hearing loss because of serous otitis media caused by eustachian tube block. Anterior bowing of the posterior maxillary wall, due to invasion of the pterygomaxillary space on axial CT, known as the Holman-Miller sign is one of the characteristic findings.

Juvenile nasopharyngeal angiofibroma

Supply of these tumours is usually via The nature of juvenile nasopharyngeal angiofibroma. Hence the patient can take oral feeds early and with less morbidity. Moorthy 1 Department of E. JNA being an aggressive tumor may recur posttreatment.

These lesions include inflammatory naeofaring, angiomatous polyps, nasopharyngeal cysts and carcinomas, soft tissue neoplasms such as papilloma, lymphoma, neurofibroma, maxillary malignancies, nasal fossa esthesioneuroblastoma, adenoid hypertrophy, cervical vertebrae cordomas and retropharyngeal ganglia tuberculosis. Contrast enhance CT scan showing JNA extending into left sphenoid sinus eroding the lateral wall of sphenoid and entering the cavernous sinus area with intracranial extradural extension.

Type I includes lesions fundamentally localized to the nasal cavity, paranasal sinus, nasopharynx, or pterygopalatine fossa. Figure 7 shows mast cells in toluidine blue stain.


Received Jul 15; Accepted Jun 1. Avid enhancement is noted on contrast-enhanced CT. Radiological investigations, like contrast enhanced CT or MRI, are helpful in staging the JNA provided they are done as close to surgery date as possible. This makes it possible to precisely stage JNA. Based on the clinical and radiological nasofarong, JNA is classified into three types. Bilateral vascular supply in juvenile nasopharyngeal angiofibromas.

The propensity of the lesion to cause life threatening complications by way of massive bleeding has led to acquisition of considerable importance in otolaryngology practice.

Int J Pediatr Otorhinolaryngol. Retrieved from ” https: It most commonly affects adolescent males and may grow into fissures of the skull and may spread to adjacent structures. The origin and development of JNA is not fully understood.

Received Apr 24; Accepted Jun 6.