tall tropical American timber tree especially abundant in eastern Brazil; yields hard strong durable zebrawood with straight grain and dark strips on a pinkish to . Gonçalo Alves ou Gonçaleiro (Astronium fraxinifolium) Família Anacardiaceae. Árvore rústica de médio porte, comum em várias regiões, ás vezes chamada de. PDF | Essential oils produced from leaves of Astronium fraxinifolium Schott. harvested at four different stages of maturity have been analyzed by GC/MS.

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In Vitro Studies 2. Sample of the wood Photograph by: Early diagnosis and treatment are important to prevent sequelae.

As it was shown in our previous study [ 26 ], the major component in essential oil obtained from P. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted fraxinifokium, distribution, and reproduction in any medium, provided the original work is properly cited.

Astronium fraxinifolium – Dictionary Definition :

The animals were also weighed during this period. A superb work, with the minor irritation that the translation from Portuguese is not of the best. Nonetheless, in some cases when mucosa, such as fraxiniflium or oral mucosa, is injured, treatment is necessary; otherwise, permanent sequelae may occur [ 7 ]. The second protocol consisted of 15 daily intralesional injections.


As it was shown in Figure 1essential oil of P. The animals were treated with leaf ethanolic extract from Astronium fraxinifolium EEF. Macrophage cell line RAW For each experiment, cells were removed from the culture medium and incubated with 0. Several studies have been published confirming much of the popular use of Plectranthus amboinicussuch as anti-inflammatory and antimicrobial activities [ 23 — 27 ].

The treatment was initiated when the lesions appeared about the 27th day. Line drawing of the flowering branch Photograph by: However, a higher number of parasites were found when the group of animals treated with the plant material was compared with the group treated with Glucantime.

Astronium fraxinifolium – Wikipedia

View at Google Scholar A. In vitro antileishmanial activity of essential oil of P. Alternatively, pentamidine and amphotericin B may fraxinifollium used. In the present study we decided to evaluate two medicinal plants, Plectranthus amboinicus and Astronium fraxinifolium.

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If you would like to support this site, please consider Donating. View at Google Scholar O. The in vitro evaluation of the antileishmanial activity of the essential oil from P.

The supernatant was discarded, and the cells were resuspended in culture medium. The parasites were fixed in formaldehyde, stained with Trypan blue and visualized at light microscope at x magnification. Despite the promising in vitro results, in vivo experiments did not reveal a good efficacy of the treatment with EOPA in mouse model. After astrobium 7th week of infection, the lesion thickness in the group treated with the plant material was below the fraxxinifolium of normal thickness.


Treatment with the Essential Oil of P.

Further, golden hamsters were infected s. The major component of the essential oil was carvacrol. In Vivo Studies 2. The animals showed a significant reduction of lesion thickness in the 6th week, but it was not comparable to the animals treated with Glucantime.

Treatment was done by administering OEPA intralesionally i. Another point to take into account is that the drugs available for CL treatment produce significant side effects due to their high toxicity and tissue drug accumulation, which includes myalgias, nausea, vomiting, cardiac arrhythmia, hepatitis, or pancreatitis [ 1213 ]. Any loss of weight was not observed in the animals treated with the plant material.

Ethanolic extracts from A. On the other hand, all the ethanolic extracts from bark, sapwood, and leaves from A. Assays were performed in triplicate.